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LRWD1 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501561183
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50-156-1183 20 μL
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Catalog No. 50-156-1183 Supplier Bethyl Laboratories, Inc Supplier No. A301868AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

Required for G1/S transition. Recruits and stabilizes the origin recognition complex (ORC) onto chromatin during G1 to establish pre-replication complex (preRC) and to heterochromatic sites in post-replicated cells. Binds a combination of DNA and histone methylation repressive marks on heterochromatin. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3 in a cooperative manner with DNA methylation. Required for silencing of major satellite repeats. May be important ORC2, ORC3 and ORC4 stability.

Specifications

Antigen LRWD1
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene LRWD1
Gene Accession No. Q8BUI3, Q9UFC0
Gene Alias CENP-33, ORCA, ORC-associated protein, centromere protein 33, leucine-rich repeat and WD repeat-containing protein 1, origin recognition complex associated, origin recognition complex-associated protein
Gene Symbols Lrwd1
Host Species Rabbit
Immunogen Between 432 and 482
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 222229, 71735
Target Species Human, Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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