LRWD1 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A301867A

Catalog No. 50-156-1179

Description

The recommended shelf life for this product is 1 year from date of receipt.

Required for G1/S transition. Recruits and stabilizes the origin recognition complex (ORC) onto chromatin during G1 to establish pre-replication complex (preRC) and to heterochromatic sites in post-replicated cells. Binds a combination of DNA and histone methylation repressive marks on heterochromatin. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3 in a cooperative manner with DNA methylation. Required for silencing of major satellite repeats. May be important ORC2, ORC3 and ORC4 stability.

Specifications

• Antigen: LRWD1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LRWD1
• Gene Alias: CENP-33, ORCA, ORC-associated protein, centromere protein 33, leucine-rich repeat and WD repeat-containing protein 1, origin recognition complex associated, origin recognition complex-associated protein
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 222229
• Content And Storage: 4° C
• Form: Liquid

• Applications: Immunoprecipitation
• Concentration: 1 mg/ml
• Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
• Gene Accession No.: Q9UFC0
• Gene Symbols: LRWD1
• Immunogen: Between 200 and 250
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG