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Invitrogen™ Ly-108 Polyclonal Antibody
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Catalog No. PIPA547560
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100 μg
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Catalog No. Quantity
PIPA547560 100 μg
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Catalog No. PIPA547560 Supplier Invitrogen™ Supplier No. PA547560
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Description

Sheep Polyclonal Antibody

Reconstitute at 0.2 mg/mL in sterile PBS.

Ly108, the mouse homologue of human SLAMF6 (signaling lymphocyte activation molecule family member 6), is expressed on NK cells, B cells, and T cells. Engagement of the Ly108 receptor enhances NK cell activity and increases the expression of IFN-gamma. This receptor plays a role in the inability of NK cells to kill Epstein Barr virus-infected B cells in X-linked lymphoproliferative disease. In Ly108 knock-out mice, CD4+ T cells show a diminished ability to produce IL-4 and exhibit defective neutrophil functions, indicating the importance of Ly108 in immune regulation and cellular function. Overall, Ly108 is crucial for modulating immune responses and maintaining effective immune cell activity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Ly-108
Applications Flow Cytometry, Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene SLAMF6
Gene Accession No. Q9ET39
Gene Alias Activating NK receptor; CD352; KAL1; KAL1b; KALI; KALIb; Ly108; Lymphocyte antigen 108; natural killer-, T- and B-cell antigen; NK-T-B-antigen; NTBA; NTB-A; NTBA receptor; RGD1561848; SF2000; SLAM family member 6; Slamf6; UNQ6123/PRO20080
Gene Symbols SLAMF6
Host Species Sheep
Immunogen Mouse myeloma cell line NS0-derived recombinant mouse NTB-A/SLAMF6 Glu31-Asn239.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 30925
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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