Tocris Bioscience™ LY 2389575 hydrochloride 

Selective negative allosteric modulator of mGlu3

Manufacturer:  Tocris Bioscience™ 4969/10

Catalog No. 49-691-0

Description

Selective negative allosteric modulator of mGlu3 (IC50 = 190 nM). Exhibits > 65-fold selectivity for mGlu3 over other mGlu receptors. Abolishes the neuroprotective action of LY 379268 against amyloid β toxicity in mixed cortical neuronal and astrocyte cell cultures.

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Specifications

• Product Type: LY 2389575 hydrochloride
• Purity: >98
• Quantity: 10mg

• Inhibitors: LY 2389575 hydrochloride
• Molecular Weight: 438.58

For Research Use Only