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Tocris Bioscience™ LY 2389575 hydrochloride

Selective negative allosteric modulator of mGlu3

Manufacturer:  Tocris Bioscience™ 4969/50

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Catalog No. 49-695-0


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Description

Description

Selective negative allosteric modulator of mGlu3 (IC50 = 190 nM). Exhibits > 65-fold selectivity for mGlu3 over other mGlu receptors. Abolishes the neuroprotective action of LY 379268 against amyloid β toxicity in mixed cortical neuronal and astrocyte cell cultures.
Specifications

Specifications

LY 2389575 hydrochloride
>98
50mg
LY 2389575 hydrochloride
438.58
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