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Tocris Bioscience™ LY 2389575 hydrochloride

Selective negative allosteric modulator of mGlu3

Supplier: Tocris Bioscience™ 4969/50

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Catalog No. 49-695-0

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Description

LY 2389575 hydrochloride is a selective negative allosteric modulator of mGlu3 (IC50 = 190 nM). Exhibits > 65-fold selectivity for mGlu3 over other mGlu receptors. Abolishes the neuroprotective action of LY 379268 against amyloid β toxicity in mixed cortical neuronal and astrocyte cell cultures.

Specifications

Purity	>98%
Product Type	LY 2389575 hydrochloride
Inhibitors	LY 2389575 hydrochloride

Quantity	50 mg
Molecular Weight (g/mol)	438.58

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Tocris Bioscience™ LY 2389575 hydrochloride

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