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  5. Tocris Bioscience™ LY 2955303

Tocris Bioscience™ LY 2955303
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Catalog No. 59845
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Quantity:
5 mg
25 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

High affinity and selective RARγ antagonist

LY 2955303 is a high affinity and selective RARγ antagonist (Ki values are 1.1 nM, >1.7 μM and >2.9 μM for RARγ, RARα and RARβ respectively). Displays analgesic efficacy in a mouse model of osteoarthritis-like joint pain.

Specifications

Chemical Name or Material 4-[5-[3,5-Bis(1,1-dimethylethyl)phenyl]-1-[4-[(4-methyl-1-piperazinyl)carbonyl]phenyl]-1H-pyrazol-3-yl]benzoic acid
CAS 1433497-19-8
Quantity 5 mg
Solubility Soluble to 20 mM in DMSO
Molecular Formula C36H42N4O3
Formula Weight 578.74
Product Type Antagonist
Purity 98%
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