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Invitrogen™ Ly-6D Monoclonal Antibody (49-H4), PE, eBioscience™
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Catalog No. 50245509
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25 μg
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50-245-509 25 μg
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Catalog No. 50-245-509 Supplier Invitrogen™ Supplier No. 12597480
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Description

Rat Monoclonal Antibody

This 49-H4 monoclonal antibody reacts with mouse Ly-6D, which is also known as ThB. This member of the Ly6 family of GPI-anchored cell surface glycoproteins is expressed on thymocytes and splenic B cells. Moreover, common lymphoid progenitor cells that express Ly-6D have been shown to commit to the B cell lineage. Expression of Ly-6D has also been associated with Rag-1 expression along with a reduced ability to differentiate into T or NK cells. Finally, reports indicate that the level of Ly-6D expression varies in different mouse strains. Applications Reported: This 49-H4 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 49-H4 antibody has been tested by flow cytometric analysis of mouse splenocytes. This can be used at less than or equal to 0.125 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser. Filtration: 0.2 μm post-manufacturing filtered.

May act as a specification marker at earliest stage specification of lymphocytes between B- and T-cell development. Marks the earliest stage of B-cell specification. [UniProt].
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Specifications

Antigen Ly-6D
Applications Flow Cytometry
Classification Monoclonal
Clone 49-H4
Concentration 0.2 mg/mL
Conjugate PE
Formulation PBS with 0.09% sodium azide; pH 7.2
Gene Ly6d
Gene Accession No. P35459
Gene Alias E48; E48 antigen; Ly61; Ly-61; LY6D; Ly-6D; lymphocyte antigen 6 complex, locus D; lymphocyte antigen 6D; Thb; thymocyte B-cell antigen
Gene Symbols Ly6d
Host Species Rat
Purification Method Affinity chromatography
Quantity 25 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17068
Target Species Mouse
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG2c κ
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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