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  6. Invitrogen™ Ly-6G/Ly-6C Monoclonal Antibody (RB6-8C5), eFluor™ 506, eBioscience™, Invitrogen™ 

Invitrogen™ Ly-6G/Ly-6C Monoclonal Antibody (RB6-8C5), eFluor™ 506, eBioscience™, Invitrogen™

Catalog No. 69593180
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69-593-182 100 μg
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Catalog No. 69-593-180 Supplier Invitrogen™ Supplier No. 69593180
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Description

Rat Monoclonal Antibody

The RB6-8C5 MAb reacts with mouse Ly-6G, a 21-25 kDa protein also known as the myeloid differentiation antigen Gr-1. A GPI-linked protein, Gr-1 is expressed by the myeloid lineage in a developmentally regulated manner in the bone marrow. While monocytes only express Gr-1 transiently during their bone marrow development, the expression of Gr-1 on bone marrow granulocytes as well as on peripheral neutrophils is a good marker for these populations. eBioscience testing indicates that in the bone marrow and lysed whole blood, the antibody clone RB6-8C5 also stains cells that express the highest levels of Ly6c (as defined by staining with antibody clone HK1.4). It is recommended that 1A8-Ly6G (cat. 9668) be used when looking at Ly-6G specific targets.

Granulocytes are a category of white blood cells characterised by the presence of granules in their cytoplasm. They are also called polymorphonuclear leukocytes (PMN or PML) because of the varying shapes of the nucleus, which is usually lobed into three segments. In common parlance, the term polymorphonuclear leukocyte often refers specifically to neutrophil granulocytes, the most abundant of the granulocytes. Granulocytes or PMN are released from the bone marrow by the regulatory complement proteins.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Ly-6G/Ly-6C
Applications Flow Cytometry
Classification Monoclonal
Clone RB6-8C5
Concentration 0.2 mg/mL
Conjugate eFluor 506
Formulation PBS with 0.09% sodium azide; pH 7.2
Gene Ly6c1
Gene Accession No. P0CW02, P0CW03, P35461
Gene Alias AA682074; AA959465; Gr1; Gr-1; Granulocyte Marker; Ly6c; Ly-6C; Ly-6C.2; Ly6c1; Ly-6C1; Ly6c2; Ly-6C2; Ly6g; Ly-6G; ly-6G.1; lymphocyte antigen 6 complex, locus C; lymphocyte antigen 6 complex, locus C1; lymphocyte antigen 6 complex, locus C2; lymphocyte antigen 6 complex, locus G; lymphocyte antigen 6C precursor (Ly-6C); lymphocyte antigen 6C1; Lymphocyte antigen 6C2; lymphocyte antigen 6G; Lymphocyte antigen Ly-6C; lymphocyte differentiation antigen; PML; PMN
Gene Symbols Ly6c1, Ly6c2, Ly6g
Host Species Rat
Purification Method Affinity chromatography
Quantity 25 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100041546, 17067, 546644
Target Species Mouse
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG2b κ
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Safety and Handling

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