Ly-6G Monoclonal Antibody (1A8-Ly6g), Brilliant Violet™ 421, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
40-496-6880	Invitrogen™ 404966880	25 μg
40-496-6882	Invitrogen™ 404966882	100 μg

Description

Ly6G (Lymphocyte antigen 6 complex locus G6D) is a component of the myeloid differentiation antigen Gr-1, together with Ly6C. The Ly6G protein has a molecular weight of approximately 21-25 kDa and is expressed by myeloid derived cells in the bone marrow. Ly6G is a good marker for detection of peripheral neutrophils, monocytes and granulocytes. Expression of Gr-1 in bone marrow correlates with granulocyte differentiation and maturation. The physiological role of Ly6G remains unclear but studies have shown its involvement in anti-tumor response, and studies with neutrophils suggest that Ly6G ligation may have an inhibitory effect on local immune responses.

Specifications

• Antigen: Ly-6G
• Concentration: 0.2 mg/mL
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with BSA and 0.09% sodium azide; pH 7.2
• Gene Alias: Gr1; Gr-1; Ly6g; Ly-6G; ly-6G.1; lymphocyte antigen 6 complex, locus G; lymphocyte antigen 6G
• Gene Symbols: Ly6g
• Primary or Secondary: Primary
• Content And Storage: 4°C, store in dark, DO NOT FREEZE!
• Gene: Ly6g

• Clone: 1A8-Ly6g
• Applications: Flow Cytometry
• Conjugate: Brilliant Violet 421
• Host Species: Rat
• Target Species: Mouse
• Gene Accession No.: P35461
• Gene ID (Entrez): 546644
• Isotype: IgG2a κ
• Purification Method: Affinity chromatography
• Product Type: Antibody