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  6. Invitrogen™ Ly-6K Monoclonal Antibody (B33fc8k), PE, eBioscience™ 

Invitrogen™ Ly-6K Monoclonal Antibody (B33fc8k), PE, eBioscience™
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Catalog No. 501122357
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100 μg
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Catalog No. Quantity
50-112-2357 100 μg
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Catalog No. 50-112-2357 Supplier Invitrogen™ Supplier No. 12592982
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Description

Rat Monoclonal Antibody

Description: This B33fc8k monoclonal antibody reacts with mouse Ly-6k, a member of the Ly6/uPAR superfamily. Ly-6k is a GPI linked protein predominantly found on the cell surface. One study suggests expression may also be non-membranous. Expression is found on B cells and reported to be on plasma cells as well as cells in the testis. Using the B33fc8k monoclonal antibody, expression is on a B lymphocyte cell subset in the spleen that correlates to transitional cells (CD23-IgM-). In humans Ly-6k has been found associated with carcinomas of the head and testis. Applications Reported: This B33fc8k antibody has been reported for use in flow cytometric analysis. Applications Tested: This B33fc8k antibody has been tested by flow cytometric analyis of mouse splenocytes. This can be used at less than or equal to 1 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser. Filtration: 0.2 μm post-manufacturing filtered.

Required for sperm migration into the oviduct and male fertility by controlling binding of sperm to zona pellucida. May play a role in cell growth (PubMed:18089789). [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen Ly-6K
Applications Flow Cytometry
Classification Monoclonal
Clone B33fc8k
Concentration 0.2 mg/mL
Conjugate PE
Formulation PBS with 0.09% sodium azide; pH 7.2
Gene LY6K
Gene Accession No. Q9CWP4
Gene Alias 2410015A16Rik; 3110035B01Rik; cancer/testis antigen 97; CO16; CT97; FLJ35226; HSJ001348; Ly6k; ly-6K; lymphocyte antigen 6 complex, locus K; lymphocyte antigen 6 complex, locus K-like; lymphocyte antigen 6K; mLy-6K; up-regulated in lung cancer 10; URLC10
Gene Symbols LY6K
Host Species Rat
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 76486
Target Species Mouse
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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