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CPC Scientific Biotin-Lys-Gly-Trp-His-Leu-Lys-Ser-Lys(Me1)-Lys-Gly-Gln-Ser-Thr-Ser-Arg-His-Lys-Lys-Leu-Met-Phe-Lys-Thr-Glu-Gly-Pro-Asp-Ser-Asp-NH2 (trifluoroacetate salt) 1MG

Supplier: CPC Scientific CANC009B

This is human tumor suppressor protein p53 (368-393) monomethylated at Lys373 and biotinylated through a KGW linker at its N-terminus. Methylation at Lys373 is catalyzed by G9a and Glp lysine methyltransferases and is associated with inactive p53. ONE-LETTER SEQUENCE: Biotin-KGWHLKS-K(Me1)-KGQSTSRHKKLMFKTEGPDSD-NH2MOLECULAR FORMULA: MOLECULAR WEIGHT:3582.2STORAGE CONDITIONS: -20 5CRESEARCH AREA: CancerREFERENCES: Krishnan, S. et al. ChemBioChem 12, 254 (2011); Huang, J. et al. J Biol Chem 285, 9636 (2010)
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