MACF1 Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A304564AT

Catalog No. 50-156-8055

Description

The recommended shelf life for this product is 1 year from date of receipt.

Isoform 2 is a F-actin-binding protein which may play a role in cross-linking actin to other cytoskeletal proteins and also binds to microtubules. Plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. Acts as a positive regulator of Wnt receptor signaling pathway and is involved in the translocation of AXIN1 and its associated complex (composed of APC, CTNNB1 and GSK3B) from the cytoplasm to the cell membrane. Has actin-regulated ATPase activity and is essential for controlling focal adhesions (FAs) assembly and dynamics. May play role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with GOLGA4. Plays a key role in wound healing and epidermal cell migration. Required for efficient upward migration of bulge cells in response to wounding and this function is primarily rooted in its ability to coordinate MT dynamics and polarize hair follicle stem cells.

Specifications

• Antigen: MACF1
• Classification: Polyclonal
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene Accession No.: Q9QXZ0, Q9UPN3
• Gene Symbols: MACF1
• Immunogen: Between 1975 and 2025
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Conjugate: Unconjugated
• Gene: MACF1
• Gene Alias: 620 kDa actin binding protein, 620 kDa actin-binding protein, ABP620, ACF7, actin cross-linking factor, actin cross-linking family protein 7, FLJ45612, FLJ46776, KIAA0465, KIAA1251, MACF, macrophin 1, macrophin 1 isoform, Macrophin-1, OFC4, trabeculin-alpha
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11426, 23499
• Content And Storage: 4° C
• Form: Liquid