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Invitrogen™ Macro H2A.2 Monoclonal Antibody (OTI1C2)
Mouse Monoclonal Antibody
Supplier: Invitrogen™ MA526593
Description
Macro H2A.2 Monoclonal Antibody for Western Blot, IHC (P)
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation.
Specifications
Macro H2A.2 | |
Monoclonal | |
1 mg/mL | |
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3 | |
Q9P0M6 | |
H2AFY2 | |
Human recombinant protein fragment corresponding to amino acids 2-261 of H2AFY2 produced in E.coli. | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG2a |
Immunohistochemistry (Paraffin), Western Blot | |
OTI1C2 | |
Unconjugated | |
H2AFY2 | |
Core histone macro-H2A.2; core histone macroH2A2.2; H2A histone family member Y2; H2A histone family, member Y2; H2AFY2; H2afy3; Histone macroH2A2; histone mH2A2; macroH2A2; mH2A2; RGD1561371 | |
Mouse | |
Affinity chromatography | |
RUO | |
55506 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
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