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Invitrogen™ Macro H2A.2 Monoclonal Antibody (OTI1C2)
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Catalog No. PIMA526593
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100 μL
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PIMA526593 100 μL
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Catalog No. PIMA526593 Supplier Invitrogen™ Supplier No. MA526593
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Mouse Monoclonal Antibody

Macro H2A.2 Monoclonal Antibody for Western Blot, IHC (P)

Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Macro H2A.2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI1C2
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene H2AFY2
Gene Accession No. Q9P0M6
Gene Alias Core histone macro-H2A.2; core histone macroH2A2.2; H2A histone family member Y2; H2A histone family, member Y2; H2AFY2; H2afy3; Histone macroH2A2; histone mH2A2; macroH2A2; mH2A2; RGD1561371
Gene Symbols H2AFY2
Host Species Mouse
Immunogen Human recombinant protein fragment corresponding to amino acids 2-261 of H2AFY2 produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55506
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a
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