Macro H2A.2 Mouse anti-Human, Clone: OTI1F6, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA526598
DescriptionVariant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|macroH2A2, core histone macro-H2A.2, core histone macroH2A2.2, histone macroH2A2, mH2A2, H2AFY2|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|Human recombit protein fragment corresponding to amino acids 2-261 of H2AFY2 produced in E.coli|
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