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Invitrogen™ Macro H2A.2 Monoclonal Antibody (OTI1F6)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA526598

Catalog No. PIMA526598


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Description

Description

Macro H2A.2 Monoclonal Antibody for Western Blot, IHC (P)

Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Macro H2A.2
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q9P0M6
H2AFY2
Human recombinant protein fragment corresponding to amino acids 2-261 of H2AFY2 produced in E.coli.
100 μL
Primary
Human
Antibody
IgG2a
Immunohistochemistry (Paraffin), Western Blot
OTI1F6
Unconjugated
H2AFY2
Core histone macro-H2A.2; core histone macroH2A2.2; H2A histone family member Y2; H2A histone family, member Y2; H2AFY2; H2afy3; Histone macroH2A2; histone mH2A2; macroH2A2; mH2A2; RGD1561371
Mouse
Affinity Chromatography
RUO
55506
-20°C, Avoid Freeze/Thaw Cycles
Liquid
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