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Macro H2A.2 Mouse anti-Human, Clone: OTI1F6, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA526598

Catalog No. PIMA526598


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Description

Description

Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation.
Specifications

Specifications

Macro H2A.2
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q9P0M6
macroH2A2, core histone macro-H2A.2, core histone macroH2A2.2, histone macroH2A2, mH2A2, H2AFY2
Mouse
IgG2a
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
55506
Immunohistochemistry (Paraffin), Western Blot
OTI1F6
Unconjugated
H2AFY2
Liquid
H2AFY2
Human recombit protein fragment corresponding to amino acids 2-261 of H2AFY2 produced in E.coli
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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