Invitrogen™ MAL Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA1085

Catalog No. PA1-085

Description

PA1-085 detects MAL from rat, mouse, xenopus and human samples. PA1-085 has been successfully used in Western blot procedures. By Western blot, this antibody detects an ~ 17 kDa protein corresponding to MAL from rat kidney extracts. The PA1-085 immunogen is a synthetic peptides corresponding to residues C(114)F D G F T Y (R/K) H Y H E N I(126) of human MAL. This peptide (Cat. # PEP-249) can be used in neutralization and control experiments.

MAL, a nonglycosylated integral membrane proteolipid, has been identified as a major internal component of glycolipid-enriched membrane (GEM) microdomains. MAL is the first integral membrane proteolipid component to have been shown as a necessary element in the cellular apical sorting apparatus for newly synthesized proteins. In its steady state this highly hydrophobic proteolipid, resides predominantly in the apical zone of polarized epithelial cells. It has also been shown in itinerant protein cycling between the plasma membrane and endosomes and in other cells. This 17-kDa proteolipid contains four putative transmembrane domains. These domains along with its protein trafficking properties are defined by the specific signals delegated by its specific amino acid sequence.

Specifications

• Antigen: MAL
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MAL
• Gene Alias: 17 kDa myelin vesicular protein; Mal; mal T-cell differentiation protein; mal, T cell differentiation protein L homeolog; mal, T-cell differentiation protein; mal.L; MALGENE; Mpv17; Mvp17; MyD88-adapter-like; myelin and lymphocyte protein; myelin and lymphocyte protein, T cell differentiation protein; myelin and lymphocyte protein, T-cell differentiation protein; NS 3; T-lymphocyte maturation-associated protein; Vip17; XELAEV_18026637mg
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 17153, 25263, 379738, 4118
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 1 mg/mL BSA and 0.05% sodium azide
• Gene Accession No.: O09198, P21145, Q64349
• Gene Symbols: MAL, mal.L
• Immunogen: Synthetic peptides corresponding to residues C(114)F D G F T Y (R/K) H Y H E N I(126) of human MAL.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Frog
• Product Type: Antibody
• Isotype: IgG