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Invitrogen™ MAN1B1 Polyclonal Antibody
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Catalog No. PA550029
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100 μL
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PA550029 100 μL
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Catalog No. PA550029 Supplier Invitrogen™ Supplier No. PA550029
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Description

Rabbit Polyclonal Antibody

The antibody detects endogenous levels of total MAN1B1 protein.

Involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation. It primarily trims a single alpha-1,2-linked mannose residue from Man9GlcNAc2 to produce Man8GlcNAc2, but at high enzyme concentrations, as found in the ER quality control compartment (ERQC), it further trims the carbohydrates to Man5-6GlcNAc2. Tremblay L.O., Glycobiology 9:1073-1078(1999) [PubMed: 10521544]. Gonzalez D.S., J. Biol. Chem. 274:21375-21386(1999) [PubMed: 10409699]. Clark H.F., Genome Res. 13:2265-2270(2003) [PubMed: 12975309].
TRUSTED_SUSTAINABILITY

Specifications

Antigen MAN1B1
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene MAN1B1
Gene Accession No. A2AJ15, Q9UKM7
Gene Alias 3.2.1.113; E430019H13Rik; endoplasmic Reticulum Class I alpha-mannosidase; endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase; endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase 1; ER alpha 1,2-mannosidase; ER alpha-1,2-mannosidase; ER mannosidase 1; ERMan1; ERManI; Gm108; MAN1B1; Man9GlcNAc2-specific processing alpha-mannosidase; man9GlcNAc2-specific-processing alpha-mannosidase; MANA-ER; Mannosidase alpha class 1B member 1; mannosidase, alpha, class 1B, member 1; MRT15; RGD1563595; RP11-350O14.2; UNQ747/PRO1477
Gene Symbols MAN1B1
Host Species Rabbit
Immunogen Synthesized peptide derived from internal of human MAN1B1.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11253, 227619
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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