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Manic Fringe/MFNG Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501982200
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50-198-2200 100 μL
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Catalog No. 50-198-2200 Supplier Bioss Supplier No. BS12390R
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Rabbit Polyclonal Antibody

This gene is a member of the fringe gene family which also includes radical and lunatic fringe genes. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling.

Specifications

Antigen Manic Fringe/MFNG
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene MFNG
Gene Accession No. O00587
Gene Alias AW546563; Beta-1,3-N-acetylglucosaminyltransferase manic fringe; EC 2.4.1.222; manic fringe homolog; MFNG; MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase; O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
Gene Symbols MFNG
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human Manic Fringe/MFNG.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4242
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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