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Invitrogen™ MAP2 Polyclonal Antibody
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Catalog No. PIPA517646
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100 μL
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PIPA517646 100 μL
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Catalog No. PIPA517646 Supplier Invitrogen™ Supplier No. PA517646
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Description

Rabbit Polyclonal Antibody

It is not recommended to aliquot this antibody. PA5-17646 was successfully used to detect MAP2 in neurons differentiated from H9 ESC derived NSCs. This antibody is not cross-reactive with tau.

MAP2 (Microtubule Associated Protein 2) exists in two high molecular weight forms (MAP2a & MAP2b) and a low molecular weight form. The expression of MAP2 is developmentally regulated and its multiple forms arise by alternative splicing of a single gene. MAP2 is involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dendrites, implicating a role in determining and stabilizing dendritic shape during neuron development. MAP2 is useful in studies of neuron structure in normal and malignant brain tissue as well as in degenerative diseases such as Alzheimer's Disease (AD).
TRUSTED_SUSTAINABILITY

Specifications

Antigen MAP2
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 73.6 μg/mL
Conjugate Unconjugated
Formulation 0.01M HEPES with 100μg/mL BSA, 0.15M NaCl, 50% glycerol and no preservative; pH 7.5
Gene Map2
Gene Accession No. P11137, P15146, P20357
Gene Alias a730034c02; AC091465.1; DKFZp686I2148; G1-397-34; MAP 2; Map2; MAP-2; map2.S; map2a; map-2a; map2ab; MAP2B; MAP2C; MAP2R; microtubule associated protein 2; microtubule associated protein 2 S homeolog; microtubule associated protein 2; microtubule-associated protein 2; microtubule associated protein 2C; microtubule-associated protein 2; microtubule-associated protein-2; Mtap2; Mtap-2; OTTHUMP00000163916; OTTHUMP00000208143; repro4; XELAEV_18047318mg; xmap2
Gene Symbols Map2
Host Species Rabbit
Immunogen Synthetic peptide corresponding to carboxy-terminal residues of human MAP2.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17756, 25595, 4133
Target Species Human, Mouse, Monkey, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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