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Invitrogen™ MARCH2 Polyclonal Antibody

Catalog No. PIPA530620
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100 μL
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PIPA530620 100 μL
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Catalog No. PIPA530620 Supplier Invitrogen™ Supplier No. PA530620

Description

Rabbit Polyclonal Antibody

Recommended positive controls: HepG2 membrane. Predicted reactivity: Mouse (94%), Rat (94%), Zebrafish (81%), Xenopus laevis (80%), Pig (95%), Bovine (91%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

MARCH2 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome-to-trans-Golgi network (TGN) trafficking (Bartee et al., 2004 [PubMed 14722266]; Nakamura et al., 2005 [PubMed 15689499]).
TRUSTED_SUSTAINABILITY

Specifications

Antigen MARCH2
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene MARCHF2
Gene Accession No. Q9P0N8
Gene Alias 9530046H09Rik; E3 ubiquitin-protein ligase MARCH2; HSPC240; MARCH2; MARCHF2; MARCH-II; membrane associated ring finger 2; membrane associated RING-CH finger protein II; membrane associated ring-CH-type finger 2; membrane-associated ring finger (C3HC4) 2; membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase; membrane-associated RING finger protein 2; Membrane-associated RING-CH protein II; RGD1306395; RING finger protein 172; RING-type E3 ubiquitin transferase MARCH2; RNF172; syntaxin-6-binding protein
Gene Symbols MARCHF2
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human MARCH2. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51257
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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