MARCKS Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Catalog No.	Quantity
50-173-5898	150 μL

Catalog No. 50-173-5898 Supplier Proteintech Group Inc Supplier No. 510871AP150UL

Description

Rabbit Polyclonal Antibody

Myristoylated alanine-rich protein kinase C substrate (MARCKS), also designated 80K or 80K-L, has been identified as a major cellular substrate for protein kinase C. Human MARCKS is a 332 amino acid protein with a calculated molecular weight of 31.534 kDa; however, it has been shown to run at 80-87 kDa on Western blot. The plasma membrane bound protein dissociates from the membrane upon phosphorylation by various PKC isoforms. In NIH/3T3 fibroblasts, PKC alpha and PKC epsilon, but not PKC delta, are responsible for MARCKS phosphorylation. MARCKS has been found to bind calmodulin, Actin and Synapsin and is a filamentous (F) Actin crosslinking protein.

Specifications

• Antigen: MARCKS
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 0.15 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene: MARCKS
• Gene Accession No.: P26645, P29966
• Gene Alias: 80K L, 80K L protein, MACS, MARCKS, PKCSL, PRKCSL
• Gene Symbols: Marcks
• Host Species: Rabbit
• Immunogen: Peptide
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 17118, 4082
• Target Species: Human, Mouse
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG