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Invitrogen™ MARVELD1 Polyclonal Antibody
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Catalog No. PIPA5109941
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100 μL
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PIPA5109941 100 μL
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Catalog No. PIPA5109941 Supplier Invitrogen™ Supplier No. PA5109941
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MLPPPPRQPP PQARAARGAV RLQRPFLRSP LGVLRLLQLL AGAAFWITIA.

MARVELD1, (MARVEL domain-containing 1), is one of the MARVEL (MAL and related proteins for vesicle trafficking and membrane link) domain-containing proteins. It is a nuclear-localized protein that is widely expressed in normal human tissues. While it has been reported to be overexpressed in colon cancer, MARVELD1 protein levels are generally lower in several primary tumors including ovary, breast, kidney, bladder and liver. This lower level of MARVELD1 expression in tumors is thought to be due to a higher methylation status of the MARVELD1 promoter as treatment of MDA-MB-361 with 5-aza-2'-deoxycytidine restores MARVELD1 expression, suggesting that loss of MARVELD1 expression may contribute to tumorgenicity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MARVELD1
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.77 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene MARVELD1
Gene Accession No. Q7TQJ1, Q9BSK0
Gene Alias AI504298; bA548K23.8; GB14; MARVD1; MARVEL (membrane-associating) domain containing 1; MARVEL domain containing 1; MARVEL domain-containing protein 1; Marveld1; MRVLDC1; putative MARVEL domain-containing protein 1; RP11-548K23.8
Gene Symbols MARVELD1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 1-50 of human MARVELD1 (NP_1136721).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 277010, 309375, 83742
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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