Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. MASH1 Monoclonal Antibody (24B7.2D11.1), Active Motif™ 

MASH1 Monoclonal Antibody (24B7.2D11.1), Active Motif™
SDP

Catalog No. p-7188722
Encompass
Change view
Click to view available options
Quantity:
10 μg
100 μg
2 product options available for selection
Product selection table with 2 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
50-199-3290 10 μg
50-199-3289 100 μg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 2 options available.
2 options
Catalog No. 50-199-3290 Supplier Active Motif Supplier No. 61272
Only null left
Add to Cart
Add to Cart

Description

Mouse Monoclonal Antibody

ASCL1 (also known as ASH1) is a basic helix-loop-helix transcription factor that is required for early development of the nervous system. Expressed in fetal brain, ASCL1 is essential for the proper development of autonomic neurons and for the survival of subsets of autonomic neurons. ASCL1 interaction with MEF-2A may regulate the expression of specific genes that are critical for the formation of distinct neuronal circuits within the central nervous system. The high level of ASCL1 expression in neuroendocrine tumors, such as medullary thyroid cancer, small cell lung cancer and lung cancer with neuroendocrine features may provide a useful marker for cancers with neuroendocrine features. Mapping to human chromosome 12, the ASCL1 gene contains a trinucleotide repeat region, making this locus a candidate for inherited disease.

Specifications

Antigen MASH1
Applications Immunohistochemistry, Western Blot
Classification Monoclonal
Clone 24B7.2D11.1
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Ascl1
Gene Accession No. P19359, Q02067
Gene Alias achaete scute protein; achaete-scute complex homolog 1; achaete-scute complex homolog 1 (Drosophila); achaete-scute complex homolog-like 1; achaete-scute complex-like 1; achaete-scute complex-like protein 1; achaete-scute family bHLH transcription factor 1; Achaete-scute homolog 1; achaete-scute homolog 1-like; AI225900; ASCL1; ASH1; ASH-1; BHLHA46; Class A basic helix-loop-helix protein 46; HASH1; KMT2H; LOC100342114; mammalian achaete scute homolog 1; Mash1; Mash-1
Gene Symbols Ascl1
Host Species Mouse
Immunogen This MASH1 antibody was raised against a full-length protein corresponding to rat MASH1.
Purification Method Protein A
Quantity 10 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17172, 64186
Target Species Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.