Cayman Chemical Mastoparn XtrIfluoroACTAt 10mg

Supplier:  Cayman Chemical 3690310 MG

An antimicrobial peptide; active against several Gram-positive and Gram-negative bacteria (MICs = 3-64 and 4-256 UG/ml, respectively) and induces permeabilization of E. coli cytoplasmic membranes by 86% at 6.4 UG/ml; induces GDP/GTP exchange by Gi and binds to calmodulin (Kd = ~0.9 nM) in cell-free assays; induces necrosis in T98G cells at 20 µM; induces degranulation of isolated rat peritoneal mast cells at 128 UG/ml; induces hemolysis of isolated sheep, chicken, and human erythrocytes; increases survival, decreases disease severity, and prevents damage to jejunal villi and crypts in a mouse model of enterohemorrhagic E. coli infection at 20 mg/kg

Catalog No. 50-291-4863