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MC 1568, Tocris Bioscience™

Catalog No. 407710
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Quantity:
10 mg
50 mg
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Catalog No. 40-771-0

Supplier: R&D Systems 4077/10

This item is not returnable. View return policy

Description

Selective HDAC class II (IIa) inhibitor

Selective inhibitor of class IIa histone deacetylases (HDACs). Exhibits tissue-selective inhibition between members of class II deacetylases in vivo; inhibits HDAC4 and HDAC5 in skeletal muscle and the heart without affecting HDAC3 activity. Arrests myogenesis through the stabilization of myocyte enhancer factor 2D (MEF2D)-HDAC3/4 complex. Displays no inhibition of class I HDAC activity or expression.

Chemical Identifiers

CAS 852475-26-4
Molecular Formula C17H15FN2O3
Molecular Weight (g/mol) 314.32
MDL Number MFCD16875423
InChI Key QRDAPCMJAOQZSU-UHFFFAOYSA-N
Synonym hdac-in-1, e-3-4-e-3-3-fluorophenyl-3-oxoprop-1-enyl-1-methyl-1h-pyrrol-2-yl-n-hydroxyacrylamide, 2e-3-4-1e-3-3-fluorophenyl-3-oxoprop-1-en-1-yl-1-methylpyrrol-2-yl-n-hydroxyprop-2-enamide, e-3-4-e-3-3-fluorophenyl-3-oxoprop-1-en-1-yl-1-methyl-1h-pyrrol-2-yl-n-hydroxyacrylamide, e-3-4-e-3-3-fluorophenyl-3-oxoprop-1-enyl-1-methylpyrrol-2-yl-n-hydroxyprop-2-enamide, 3-5-3-3-fluorophenyl-3-oxopropen-1-yl-1-methyl-1h-pyrrol-2-yl-n-hydroxy-2-propenamide, mc1568 inverted exclamation marky hplc, 3-4-3-3-fluorophenyl-3-oxoprop-1-enyl-1-methyl-1h-pyrrol-2-yl-n-hydroxyacrylamide, e-3-4-e-3-3-fluorophenyl-3-oxoprop-1-enyl-1-methyl-1hpyrrol-2-yl-n-hydroxyacrylamide, e-3-4-3-3-fluoro-phenyl-3-oxo-propenyl-1-methyl-1h-pyrrol-2-yl-n-hydroxy-acrylamide
PubChem CID 11381449
IUPAC Name 3-{4-[3-(3-fluorophenyl)-3-oxoprop-1-en-1-yl]-1-methyl-1H-pyrrol-2-yl}-N-hydroxyprop-2-enamide
SMILES CN1C=C(C=CC(=O)C2=CC(F)=CC=C2)C=C1C=CC(=O)NO

Specifications

Quantity 10 mg
Formula Weight 314.31
Percent Purity >96%
Chemical Name or Material MC 1568

Safety and Handling

Recommended Storage Store at +4°C
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