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MC 1568, Tocris Bioscience™

Catalog No. 407750
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Quantity:
10 mg
50 mg
Catalog No. Quantity
40-775-0 50 mg
40-771-0 10 mg
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Catalog No. 40-775-0

Supplier: R&D Systems 4077/50

Item Discontinued This item has been discontinued by the supplier. Please to view product availability in your area.

This item is not returnable. View return policy

Description

Selective HDAC class II (IIa) inhibitor

Selective inhibitor of class IIa histone deacetylases (HDACs). Exhibits tissue-selective inhibition between members of class II deacetylases in vivo; inhibits HDAC4 and HDAC5 in skeletal muscle and the heart without affecting HDAC3 activity. Arrests myogenesis through the stabilization of myocyte enhancer factor 2D (MEF2D)-HDAC3/4 complex. Displays no inhibition of class I HDAC activity or expression.

Chemical Identifiers

CAS 852475-26-4
Molecular Formula C17H15FN2O3
Molecular Weight (g/mol) 314.32
MDL Number MFCD16875423
InChI Key QRDAPCMJAOQZSU-UHFFFAOYSA-N
Synonym hdac-in-1, e-3-4-e-3-3-fluorophenyl-3-oxoprop-1-enyl-1-methyl-1h-pyrrol-2-yl-n-hydroxyacrylamide, 2e-3-4-1e-3-3-fluorophenyl-3-oxoprop-1-en-1-yl-1-methylpyrrol-2-yl-n-hydroxyprop-2-enamide, e-3-4-e-3-3-fluorophenyl-3-oxoprop-1-en-1-yl-1-methyl-1h-pyrrol-2-yl-n-hydroxyacrylamide, e-3-4-e-3-3-fluorophenyl-3-oxoprop-1-enyl-1-methylpyrrol-2-yl-n-hydroxyprop-2-enamide, 3-5-3-3-fluorophenyl-3-oxopropen-1-yl-1-methyl-1h-pyrrol-2-yl-n-hydroxy-2-propenamide, mc1568 inverted exclamation marky hplc, 3-4-3-3-fluorophenyl-3-oxoprop-1-enyl-1-methyl-1h-pyrrol-2-yl-n-hydroxyacrylamide, e-3-4-e-3-3-fluorophenyl-3-oxoprop-1-enyl-1-methyl-1hpyrrol-2-yl-n-hydroxyacrylamide, e-3-4-3-3-fluoro-phenyl-3-oxo-propenyl-1-methyl-1h-pyrrol-2-yl-n-hydroxy-acrylamide
PubChem CID 11381449
IUPAC Name 3-{4-[3-(3-fluorophenyl)-3-oxoprop-1-en-1-yl]-1-methyl-1H-pyrrol-2-yl}-N-hydroxyprop-2-enamide
SMILES CN1C=C(C=CC(=O)C2=CC(F)=CC=C2)C=C1C=CC(=O)NO

Specifications

Quantity 50 mg
Formula Weight 314.31
Percent Purity >96%
Chemical Name or Material MC 1568

Safety and Handling

Recommended Storage Store at +4°C
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