Invitrogen™ MC1R Monoclonal Antibody (578CT6.2.3)

Catalog No.	Quantity
PIMA537591	400 μL

Catalog No. PIMA537591 Supplier Invitrogen™ Supplier No. MA537591

Description

Mouse Monoclonal Antibody

MC1R Monoclonal Antibody for Western Blot

MC1R, a Melanocortin Receptor, mediates the effects of melanocyte-stimulating hormone (MSH) and adrenocorticotropic hormone (ACTH). MSH and its receptor, MC1R, are key regulators of melanogenesis. They control the relative proportions of red pheomelanin and black photoprotective eumelanin in the skin by increasing the production of eumelanin. Non-functional, truncated forms of the receptor lead to lighter coat color in animals. In contrast, constitutively active receptors lead to darker color.

Specifications

• Antigen: MC1R
• Applications: Western Blot
• Classification: Monoclonal
• Clone: 578CT6.2.3
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene: Mc1r
• Gene Accession No.: Q01726
• Gene Alias: alpha melanocyte stimulating hormone receptor; CMM5; e; extension recessive yellow; MC1 receptor; MC1R; MC1-R; melanocortin 1 receptor; melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor); melanocortin receptor 1; melanocortin-1 receptor; melanocyte-stimulating hormone receptor; melanotropin receptor; MSHR; MSH-R; Mshra; SHEP2; Tob; tobacco darkening
• Gene Symbols: Mc1r
• Host Species: Mouse
• Immunogen: KLH conjugated synthetic peptide between 205-232 amino acids from the Central region of human MC1R.
• Purification Method: Euglobulin precipitation
• Quantity: 400 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4157
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgM