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Invitrogen™ MC1R Polyclonal Antibody
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Catalog No. PIPA595418
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100 μg
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PIPA595418 100 μg
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Catalog No. PIPA595418 Supplier Invitrogen™ Supplier No. PA595418
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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: PC12 whole cell, HEPA1-6 whole cell, HELA whole cell, A375 whole cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

MC1R, a Melanocortin Receptor, mediates the effects of melanocyte-stimulating hormone (MSH) and adrenocorticotropic hormone (ACTH). MSH and its receptor, MC1R, are key regulators of melanogenesis. They control the relative proportions of red pheomelanin and black photoprotective eumelanin in the skin by increasing the production of eumelanin. Non-functional, truncated forms of the receptor lead to lighter coat color in animals. In contrast, constitutively active receptors lead to darker color.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MC1R
Applications Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and 0.05mg sodium azide
Gene Mc1r
Gene Accession No. Q01726, Q01727
Gene Alias alpha melanocyte stimulating hormone receptor; CMM5; e; extension recessive yellow; MC1 receptor; MC1R; MC1-R; melanocortin 1 receptor; melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor); melanocortin receptor 1; melanocortin-1 receptor; melanocyte-stimulating hormone receptor; melanotropin receptor; MSHR; MSH-R; Mshra; SHEP2; Tob; tobacco darkening
Gene Symbols Mc1r
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence at the C-terminus of human MC1 Receptor (290-317aa NAIIDPLIYAFHSQELRRTLKEVLTCSW).
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 102552838, 17199, 4157
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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Safety and Handling

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