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CPC Scientific MCA-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys(DNP)-NH2 (acetate salt) 0.5MG

Supplier: CPC Scientific AMYD108A

Fluorogenic substrate for pro-memapsin-2 containing the b-secretase site of the Swedish mutation of APP. The kinetic parameters at pH 4.5 are Km = 4.5 ?M and kcat = 0.25 min-1.ONE-LETTER SEQUENCE: Mca-SEVNLDAEF-K(DNP)-NH2MOLECULAR FORMULA: C68H89N15O26MOLECULAR WEIGHT:1532.54STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [1802078-32-5], SYNONYMS: Mca-(Asn,Leu)-Amyloid β/A4 Protein Precursor (667-675)-Lys(Dnp) amideRESEARCH AREA: Alzheimer's DiseaseREFERENCES: J. Ermolieff et al., Biochemistry, 39, 16263 (2000); J. Ermolieff et al., Biochemistry, 39, 12450 (2000)
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