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Invitrogen™ MDFI Polyclonal Antibody
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Catalog No. PIPA536599
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100 μL
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PIPA536599 100 μL
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Catalog No. PIPA536599 Supplier Invitrogen™ Supplier No. PA536599
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Description

Rabbit Polyclonal Antibody

This antibody detects endogenous protein at a molecular weight of 25 kDa. Purity is >95% by SDS-PAGE.

MDFI is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures. MDFI an also interfere with the DNA-binding activity of Myod family members and plays an important role in trophoblast and chondrogenic differentiation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MDFI
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene Mdfi
Gene Accession No. P70331, Q99750
Gene Alias I-mf; I-mfa; inhibitor of MyoD family a; MDFI; MyoD family inhibitor; myogenic repressor I-mf; RGD1560271
Gene Symbols Mdfi
Host Species Rabbit
Immunogen Synthetic peptide corresponding to amino acids 100-146 of human MDFI.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17240, 4188, 501097
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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