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Invitrogen™ MDFI Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA536599

Catalog No. PIPA536599


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Description

Description

This antibody detects endogenous protein at a molecular weight of 25 kDa. Purity is >95% by SDS-PAGE.

MDFI is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures. MDFI an also interfere with the DNA-binding activity of Myod family members and plays an important role in trophoblast and chondrogenic differentiation.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

MDFI
Polyclonal
Unconjugated
Mdfi
I-mf; I-mfa; inhibitor of MyoD family a; MDFI; MyoD family inhibitor; myogenic repressor I-mf; RGD1560271
Rabbit
Antigen affinity chromatography
RUO
17240, 4188, 501097
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Western Blot, Immunocytochemistry
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
P70331, Q99750
Mdfi
Synthetic peptide corresponding to amino acids 100-146 of human MDFI.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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