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  8. Meclizine dihydrochloride monohydrate, Thermo Scientific™

Meclizine dihydrochloride monohydrate, Thermo Scientific™

Catalog No. AAJ6246403
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Catalog No. AAJ6246403 Supplier Thermo Scientific Chemicals Supplier No. J6246403

Description

Antiemetic and H1-histamine receptor antagonist

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

Applications
Antiemetic and H1-histamine receptor antagonistMeclizine dihydrochloride monohydrate acts as an antiemetic. It is also used for the prevention and treatment of nausea during pregnancy. In addition to this, it is used in radiation sickness, vomiting or dizziness associated with motion sickness.

Solubility
Insoluble in water.

Notes
Incompatible with heat and oxidizing agents.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 31884-77-2
Molecular Formula C25H31Cl3N2O
Molecular Weight (g/mol) 481.886
MDL Number MFCD00058199
InChI Key KDLHYOMCWBWLMM-UHFFFAOYSA-N
Synonym meclizine hydrochloride, meclizine dihydrochloride monohydrate, meclizine hcl, antivert tn, c25h27cln2.2hcl.h2o, 1-p-chloro-alpha-phenylbenzyl-4-m-methylbenzyl piperazine dihydrochloride monohydrate, 1-4-chlorophenyl-phenylmethyl-4-3-methylphenyl methyl piperazine hydrate dihydrochloride, piperazine, 1-4-chlorophenyl phenylmethyl-4-3-methylphenyl methyl-, dihydrochloride, monohydrate, meclizine hcl hydrate, meclizine hydrochloride usan:jan
PubChem CID 173612
IUPAC Name 1-[(4-chlorophenyl)-phenylmethyl]-4-[(3-methylphenyl)methyl]piperazine;hydrate;dihydrochloride
SMILES CC1=CC(=CC=C1)CN2CCN(CC2)C(C3=CC=CC=C3)C4=CC=C(C=C4)Cl.O.Cl.Cl

Specifications

Melting Point 210°C to 213°C
Color White
Quantity 1 g
Merck Index 14,5777
Solubility Information Insoluble in water.
Formula Weight 481.89 (463.88 Anhydrous)
Physical Form Powder
Chemical Name or Material Meclizine dihydrochloride monohydrate

Safety and Handling

Hazard Category H302-H361
Hazard Statement GHS H Statement
H361-H302
Suspected of damaging fertility or the unborn child.
Harmful if swallowed.
Precautionary Statement P201-P202-P264b-P270-P281-P301+P312-P308+P313-P330-P501c
TSCA Yes
Recommended Storage Store at -20°C
SDS
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