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Invitrogen™ MECR Polyclonal Antibody
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Catalog No. PIPA534490
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100 μg
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Catalog No. Quantity
PIPA534490 100 μg
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Catalog No. PIPA534490 Supplier Invitrogen™ Supplier No. PA534490
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Description

Rabbit Polyclonal Antibody

A suggested positive control is human brain tissue lysate. PA5-34490 can be used with blocking peptide PEP-1532.

The mitochondrial trans-2-enoyl-CoA reductase (MECR), was initially identified as nuclear receptor-binding factor 1 (NRBF1), which can interact with a multitude of nuclear hormone receptors in the presence of the respective ligands. MECR has been shown to be part of the mitochondrial fatty acid synthesis (FAS II) system and to catalyze the NAPDH-dependent reduction of 2-enoyl thioesters, generating saturated acyl-groups. Overexpression of this gene in transgenic mice can lead to cardiac abnormalities, suggesting that inappropriate expression of genes of FAS II can result in the development of hereditary cardiomyopathy.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MECR
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene Mecr
Gene Accession No. Q9BV79, Q9DCS3, Q9Z311
Gene Alias 2-enoyl thioester reductase; AI195831; CGI-63; Enoyl-[acyl-carrier-protein] reductase, mitochondrial; FASN2B; homolog of yeast 2-enoyl thioester reductase; HsNrbf-1; Mecr; mitochondrial 2-enoyl thioester reductase; mitochondrial trans-2-enoyl-CoA reductase; NBRF1; Nrbf1; NRBF-1; nuclear receptor binding factor 1; nuclear receptor-binding factor 1; trans-2-enoyl-CoA reductase, mitochondrial
Gene Symbols Mecr
Host Species Rabbit
Immunogen A 15 amino acid peptide near the carboxy terminus of human MECR.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 26922, 29470, 51102
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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