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Mecr Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 501735855 Shop All Proteintech Group Inc Products
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50-173-5855 150 μL
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Catalog No. 50-173-5855 Supplier Proteintech Group Inc Supplier No. 510272AP150UL
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Description

Rabbit Polyclonal Antibody

The mitochondrial trans-2-enoyl-CoA reductase (MECR), was initially identified as nuclear receptor-binding factor 1 (NRBF1), which can interact with a multitude of nuclear hormone receptors in the presence of the respective ligands. MECR has been shown to be part of the mitochondrial fatty acid synthesis (FAS II) system and to catalyze the NAPDH-dependent reduction of 2-enoyl thioesters, generating saturated acyl-groups. Overexpression of this gene in transgenic mice can lead to cardiac abnormalities, suggesting that inappropriate expression of genes of FAS II can result in the development of hereditary cardiomyopathy.

Specifications

Antigen Mecr
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.17 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene MECR
Gene Accession No. Q9BV79, Q9DCS3, Q9Z311
Gene Alias AI195831, Mecr, Nrbf1
Gene Symbols Mecr
Host Species Rabbit
Immunogen Mecr Fusion Protein Ag0465
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 26922, 29470, 51102
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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