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MED12 Rabbit anti-Human, Mouse, Polyclonal, Bethyl Laboratories
Rabbit Polyclonal Antibody
Supplier: Bethyl Laboratories, Inc A300774A

Description
The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections. Based on 100% sequence identity, this antibody is predicted to react with Chimpanzee
The initiation of transcription is controlled in part by a large protein assembly known as the preinitiation complex. A component of this preinitiation complex is a 1.2 MDa protein aggregate called Mediator. This Mediator component binds with a CDK8 subcomplex which contains the protein encoded by this gene, mediator complex subunit 12 (MED12), along with MED13, CDK8 kinase, and cyclin C. The CDK8 subcomplex modulates Mediator-polymerase II interactions and thereby regulates transcription initiation and reinitation rates. The MED12 protein is essential for activating CDK8 kinase. Defects in this gene cause X-linked Opitz-Kaveggia syndrome, also known as FG syndrome, and Lujan-Fryns syndrome. [provided by RefSeq, Aug 2009].Specifications
MED12 | |
Polyclonal | |
Unconjugated | |
MED12 | |
Kiaa0192, Mopa, Tnrc11, Trap230 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
59024, 9968 | |
4° C | |
Liquid |
Immunohistochemistry, Immunoprecipitation, Western Blot | |
1 mg/ml | |
phosphate, tris citrate with 0.09% sodium azide; pH 7-8 | |
A2AGH6, Q93074 | |
MED12 | |
Between 2150 and C-term | |
100 μL | |
Primary | |
Human, Mouse | |
Antibody | |
IgG |
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