MED15 Monoclonal Antibody (OTI1H5), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA807919

Catalog No. 50-168-1845

Description

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for cholesterol-dependent gene regulation. Positively regulates the Nodal signaling pathway.

Specifications

• Antigen: MED15
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q96RN5
• Gene Symbols: MED15
• Immunogen: Human recombit protein fragment corresponding to amino acids 393-679 of human MED15 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI1H5
• Conjugate: Unconjugated
• Gene: MED15
• Gene Alias: ARC105, CAG7A, CTG7A, PCQAP, TIG-1, TIG1, TNRC7
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51586
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid