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MEF2C Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 182901AP

Catalog No. 50-173-2093


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Description

Description

The antibody can recognize the transcript variant 1 and transcript variant 3 of MEF2C.

MEF2C is a transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex. Necessary for proper development of megakaryocytes and platelets and for bone marrow B lymphopoiesis. Required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B cells. May also be involved in neurogenesis and in the development of cortical architecture. Isoform 3 and isoform 4, which lack the repressor domain, are more active than isoform 1 and isoform 2.
Specifications

Specifications

MEF2C
0.26 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q06413, Q8CFN5
MEF2C, myocyte enhancer factor 2C
Rabbit
IgG
150 μL
-20°C
Primary
17260, 4208, 499497
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
MEF2C
Liquid
Mef2c
Peptide
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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