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Invitrogen™ MEGF10 Polyclonal Antibody
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Catalog No. PIPA587956 Shop All Thermo Scientific Products
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PIPA587956 100 μL
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Catalog No. PIPA587956 Supplier Invitrogen™ Supplier No. PA587956
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Description

Rabbit Polyclonal Antibody

Positive Samples: U-251MG, HT-29, MCF7, Mouse brain, Mouse liver, Rat brain; Cellular Location: Basolateral cell membrane, Cell membrane, Cell projection, Single-pass type I membrane protein, phagocytic cup Immunogen sequence: ADYTISGTLP HSNGGNANSH YFTNPSYHTL TQCATSPHVN NRDRMTVTKS KNNQLFVNLK NVNPGKRGPV GDCTGTLPAD WKHGGYLNEL GAFGLDRSYM GKSLKDLGKN SEYNSSNCSL SSSENPYATI KDPPV.

This gene encodes a member of the multiple epidermal growth factor-like domains protein family. The encoded protein plays a role in cell adhesion, motility and proliferation, and is a critical mediator of apoptotic cell phagocytosis as well as amyloid-beta peptide uptake in the brain. Expression of this gene may be associated with schizophrenia, and mutations in this gene are a cause of early-onset myopathy, areflexia, respiratory distress, and dysphagia (EMARDD) as well as congenital myopathy with minicores. Alternatively spliced transcript variants have been observed for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MEGF10
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene MEGF10
Gene Accession No. Q6DIB5, Q96KG7
Gene Alias 3000002B06Rik; EMARDD; Gm331; KIAA1780; MEGF10; multiple EGF like domains 10; multiple EGF-like domains 10; multiple EGF-like domains protein 10; multiple EGF-like-domains 10; multiple epidermal growth factor-like domains protein 10
Gene Symbols MEGF10
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 26-160 of human MEGF10 (NP_1158221).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 291445, 70417, 84466
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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