MEI-1 Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-7231	100 μL

Catalog No. 50-198-7231 Supplier Bioss Supplier No. BS6387R

Description

Rabbit Polyclonal Antibody

The predominant cause of spermatogenic arrest of meiosis is the failure of homologous chromosomes to accurately synapse. MEI1 (Meiosis inhibitor protein 1), also designated Meiosis defective protein 1, is a 1274 amino acid protein that is likely required for the formation of genetically programmed double-strand breaks, the first step in the initiation of meiosis. With predominant expression in testis, it is likely that defects of the gene encoding MEI1 results in male infertility. Interestingly, studies show that genetic variation in the MEI gene possibly predisposes European Americans but not Israeli men to infertility by meiotic arrest. Human MEI1 shares 79% sequence similarity with its mouse homolog. There are seven isoforms of MEI1 that are produced as a result of alternative splicing events.

Specifications

• Antigen: MEI-1
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: MEI1
• Gene Accession No.: Q5TIA1
• Gene Alias: 4932408F18Rik; Mei1; meiosis defective 1; Meiosis defective protein 1; meiosis inhibitor 1; Meiosis inhibitor protein 1; meiotic double-stranded break formation protein 1; SPATA38; spermatogenesis associated 38
• Gene Symbols: MEI1
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human MEI-1.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 150365
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG