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MEK1 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501561871
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50-156-1871 20 μL
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Catalog No. 50-156-1871 Supplier Bethyl Laboratories, Inc Supplier No. A302140AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections. Based on 100% sequence identity, this antibody is predict

MAP2K1 (MEK1) is a dual specificity mitogen-activated protein kinase (MAPK) kinase. It is an essential component of the MAP kinase pathway and stimulates the enzymatic activity of MAP kinases in response to various signals. Growth factors, cytokines, and proto-oncogenes transduce their signals through the activation of RAS, which leads to activation of the serine/threonine kinase RAF, and then to activation of MAPK kinase. MAP2K1 is activated by the Raf family member p74raf-1, through phosphorylation of serine residues at positions 217 and 221 in the activation loop.

Specifications

Antigen MEK1
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene MAP2K1
Gene Accession No. Q02750
Gene Alias MAPKK1, MEK1, MKK1, PRKMK1
Gene Symbols MAP2K1
Host Species Rabbit
Immunogen Between 343 and 393
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5604
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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