Melanophilin Mouse anti-Human, Porcine, Clone: 1A8D12, Proteintech

Mouse Monoclonal Antibody

Supplier:  Proteintech Group Inc 660921IG150UL

Catalog No. 50-173-6528

Description

Slac2-a (for synaptotagmin-like protein (Slp) homolog lacking C2 domains-a) links Rab27A on melanosomes with Myosin VA in melanocytes. Slac2-a binds Myosin VA through a C-terminal region and GTP-bound Rab27A through its synaptotagmin-like protein homology domain (SHD), which is located near the N-terminus. The transport of pigment and cytotoxic granules in melanocytes requires the stable formation of this complex, and thus mutations in the binding domains of the three protein components may cause albinism and/or severe immune disorders.

Specifications

• Antigen: Melanophilin
• Classification: Monoclonal
• Concentration: 0.77 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9BV36
• Gene Symbols: MLPH
• Immunogen: Melanophilin Fusion Protein Ag19286
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Pig
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Clone: 1A8D12
• Conjugate: Unconjugated
• Gene: MLPH
• Gene Alias: Exophilin 3, melanophilin, MLPH, SLAC2 A, SLAC2A, Synaptotagmin like protein 2a
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 100049680, 79083
• Content And Storage: -20°C
• Form: Liquid