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  6. Melanophilin Mouse anti-Human, Porcine, Clone: 1A8D12, Proteintech 

Melanophilin Mouse anti-Human, Porcine, Clone: 1A8D12, Proteintech
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Catalog No. 501736528 Shop All Proteintech Group Inc Products
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50-173-6528 150 μL
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Catalog No. 50-173-6528 Supplier Proteintech Group Inc Supplier No. 660921IG150UL
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Description

Mouse Monoclonal Antibody

Slac2-a (for synaptotagmin-like protein (Slp) homolog lacking C2 domains-a) links Rab27A on melanosomes with Myosin VA in melanocytes. Slac2-a binds Myosin VA through a C-terminal region and GTP-bound Rab27A through its synaptotagmin-like protein homology domain (SHD), which is located near the N-terminus. The transport of pigment and cytotoxic granules in melanocytes requires the stable formation of this complex, and thus mutations in the binding domains of the three protein components may cause albinism and/or severe immune disorders.

Specifications

Antigen Melanophilin
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 1A8D12
Concentration 0.77 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene MLPH
Gene Accession No. Q9BV36
Gene Alias Exophilin 3, melanophilin, MLPH, SLAC2 A, SLAC2A, Synaptotagmin like protein 2a
Gene Symbols MLPH
Host Species Mouse
Immunogen Melanophilin Fusion Protein Ag19286
Purification Method Protein G
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100049680, 79083
Target Species Human, Pig
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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