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CPC Scientific H-Gly-Ile-Gly-Ala-Val-Leu-Lys-Val-Leu-Thr-Thr-Gly-Leu-Pro-Ala-Leu-Ile-Ser-Trp-Ile-Lys-Arg-Lys-Arg-Gln-Gln-NH2 (trifluoroacetate salt) 1MG
SDP

Supplier:  CPC Scientific PKCP018B

Encompass

26-residue polypeptide isolated from bee venom that binds calmodulin in a Ca2+ dependent manner, activates phospholipase A2, and inhibits protein kinase C (IC50 = 5-7 m M) by binding to the catalytic domain in a Mg-ATP sensitive manner. IC50 of 1-4 µM.ONE-LETTER SEQUENCE: GIGAVLKVLTTGLPALISWIKRKRQQ-NH2MOLECULAR FORMULA: C131H229N39O31MOLECULAR WEIGHT:2846.46STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [20449-79-0], RESEARCH AREA: Protein Kinases and PhosphatasesREFERENCES: Raynor et al., J. Biol. Chem., 266, 2753 (1991); Schweitz, Toxicon, 22, 308 (1984)

Catalog No. 50-211-0171


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