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Menin Rabbit anti-Human, Mouse, Polyclonal, Bethyl Laboratories

Catalog No. 501556907
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50-155-6907 100 μL
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Catalog No. 50-155-6907 Supplier Bethyl Laboratories, Inc Supplier No. A300105A
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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections. Based on 100% sequence identity, this antibody is predicted to react with Rat, Bovine and Dog

Menin is a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. In vitro studies have shown menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD, however, the function of this protein is not known. Two messages have been detected on northern blots but the larger message has not been characterized. Two variants of the shorter transcript have been identified where alternative splicing affects the CDS. Five variants where alternative splicing takes place in the 5′ UTR have also been identified.

Specifications

Antigen Menin
Applications Immunohistochemistry, Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene MEN1
Gene Accession No. O00255, O88559
Gene Alias MEAI, menin, multiple endocrine neoplasia I, SCG2
Gene Symbols MEN1
Host Species Rabbit
Immunogen Between 575 and C-term
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17283, 4221
Target Species Human, Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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