Invitrogen™ Metallothionein Monoclonal Antibody (UC1MT)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA125479

Catalog No. MA125479

Description

A band of approximately 15 kDa is detected. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene is a member of the metallothionein family of genes. Proteins encoded by this gene family are low in molecular weight, are cysteine-rich, lack aromatic residues, and bind divalent heavy metal ions. The conserved cysteine residues co-ordinate metal ions using mercaptide linkages. These proteins act as anti-oxidants, protect against hydroxyl free radicals, are important in homeostatic control of metal in the cell, and play a role in detoxification of heavy metals. Disruption of two metallothionein genes in mouse resulted in defects in protection against heavy metals, oxidative stress, immune reactions, carcinogens, and displayed obesity. MT1A (Metallothionein 1A) is a Protein Coding gene. Diseases associated with MT1A include Menkes Disease and Deficiency Anemia. Among its related pathways are Metal ion SLC transporters and Cellular responses to stimuli. An important paralog of this gene is MT2A.

Specifications

• Antigen: Metallothionein
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.2
• Gene Accession No.: P04731, P11957
• Gene Symbols: MT1A
• Immunogen: Full length protein from cross linked rabbit liver MT1 and MT2.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Rabbit, Horse, Fish
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: UC1MT
• Conjugate: Unconjugated
• Gene: MT1A
• Gene Alias: Metallothionein; Metallothionein-1
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 100343802, 4489
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid