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Tocris Bioscience™ Metformin hydrochloride
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Catalog No. 2864100
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28-641-00 100 mg
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Activator of LKB1/AMPK; antidiabetic agent

Metformin hydrochloride is an antidiabetic agent; lowers plasma glucose levels and improves insulin sensitivity. Inhibits hepatic gluconeogenesis via activation of the LKB1/AMPK pathway. Displays antiproliferative effects in cancer cell lines via inhibition of mitochondrial complex I (MRC-1). Activates the aPKC-CBP pathway in neural precursors to promote neurogenesis. Activates autophagy. Identified by chemoinformatics as targeting human host proteins that interact with SARS-CoV-2.

Chemical Identifiers

CAS 1115-70-4
Molecular Formula C4H12ClN5

Specifications

Quantity 100 mg
Formula Weight 165.62
Purity >98%
Molecular Weight (g/mol) 165.63
Chemical Name or Material Metformin hydrochloride
Recommended Storage Store at Room Temperature
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