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Lkt Laboratories CAS 6745-93-3, ≥98%, DHF reductase inhibitor used to treat rheumatoid arthritis, ectopic pregnancy, and various cancers. It prevents synthesis of thymidine, RNA, and RNA.

Supplier: Lkt Laboratories M1676

Methotrexate is an antimetabolite that exhibits immunosuppressive, abortifacient, anti-inflammatory, and anticancer chemotherapeutic activities. Methotrexate is clinically used to treat various cancers, ectopic pregnancy, and rheumatoid arthritis. Methotrexate inhibits dihydrofolate reductase, preventing thymidine, DNA, and RNA synthesis. In vivo, methotrexate increases T cell apoptosis, decreases T cell activation, and suppresses cytokine production.
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