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Methylprednisolone, Tocris Bioscience™

Catalog No. 481950
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Quantity:
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Glucocorticoid receptor agonist

Glucocorticoid receptor (GR) agonist. Displays anti-inflammatory and antioxidant properties. Attenuates apoptosis in oligodendrocytes after injury stimuli. Upregulates expression of Bcl-xL via direct binding of the GR/STAT5 complex. Neuroprotective.

Chemical Identifiers

CAS 83-43-2
Molecular Formula C22H30O5
Molecular Weight (g/mol) 374.48
MDL Number MFCD00010591
InChI Key VHRSUDSXCMQTMA-PJHHCJLFSA-N
Synonym methylprednisolone, medrol, medrone, urbason, methylprednisolon, 6alpha-methylprednisolone, metilbetasone, medrate, metilprednisolone, dopomedrol
PubChem CID 6741
ChEBI CHEBI:6888
IUPAC Name (1R,3aS,3bS,5S,9aR,9bS,10S,11aS)-1,10-dihydroxy-1-(2-hydroxyacetyl)-5,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one
SMILES C[C@H]1C[C@H]2[C@@H]3CC[C@](O)(C(=O)CO)[C@@]3(C)C[C@H](O)[C@@H]2[C@@]2(C)C=CC(=O)C=C12

Specifications

Quantity 50 mg
Formula Weight 374.47
Percent Purity >99%
Chemical Name or Material Methylprednisolone
Recommended Storage Store at +4°C
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