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  6. Invitrogen™ METTL15P1 Recombinant Mouse Monoclonal Antibody (K1H006_6E6) 

Invitrogen™ METTL15P1 Recombinant Mouse Monoclonal Antibody (K1H006_6E6)

Catalog No. MA565963
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MA565963 50 μL
MA564504 100 μL
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Catalog No. MA565963 Supplier Invitrogen™ Supplier No. MA565963
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Description

Mouse Recombinant Monoclonal Antibody

Immunogen sequence: QTQVQELHRS QDRDFETMAK LHIPVMVDEV VHCLSPQKGQ IFLDMTFGSG GHTKAILQKE SDIVLYALDR DPTAYALAEH LSELYPKQIR AMLGQFSQAE ALLMKAGVQP GTFDGVLMDL GCSSMQLDTP ERGSSLRKDG PLDIRMDGGR Highest antigen sequence identity to the following orthologs: Mouse - 79%, Pig - 87%, Cynomolgus monkey - 96%.

METTL15P1 is a pseudogene related to the METTL15 gene, which encodes a methyltransferase responsible for methylation of mitochondrial 12S rRNA at m4C839 both in vivo and in vitro. The METTL15 protein is involved in fine-tuning gene expression, particularly during differentiation processes in cells, as part of the METTL3-METTL14-DNMT1 axis, which is crucial for regulating expression of key differentiation genes in embryonic stem cells. Additionally, METTL15 is linked to the regulation of the mitochondrial genome, influencing stress-specific responses and contributing to an information-rich genotype-phenotype map that elucidates gene function and cellular dynamics. While pseudogenes like METTL15P1 do not encode functional proteins, they may still play roles in gene regulation and the broader genomic context. The study of METTL15P1 could potentially reveal insights into the evolutionary history of RNA methylation and its impact on cellular processes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen METTL15P1
Applications Western Blot
Classification Recombinant Monoclonal
Clone K1H006_6E6
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.5% BSA, 50% glycerol and 0.09% sodium azide
Gene METTL15P1
Gene Accession No. P0C7V9
Gene Symbols METTL15P1
Host Species Mouse
Immunogen Recombinant human METTL15P1 (aa 51-200).
Purification Method Protein A
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100130758
Target Species Human, Mouse
Content And Storage Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG2a
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