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MFN2 Mouse anti-Human, Mouse, Rat, Clone: S153-5, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA527647

Catalog No. PIMA527647


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Description

Description

This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintece and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.
Specifications

Specifications

MFN2
Monoclonal
1 mg/ml
PBS with 50% glycerol and 0.1% sodium azide; pH 7.4
O95140, Q80U63, Q8R500
CMT2A, CMT2A2, CPRP 1, CPRP1, Fzo, HSG, hyperplasia suppressor gene, Hypertension related protein 1, KIAA0214, MARF, MFN 2, Mfn2, Mitochondrial assembly regulatory factor, Mitofusin-2, Mitofusin2, Transmembrane GTPase MFN2
Mouse
IgG2a
100 μg
-20°C
Primary
170731, 64476, 9927
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot
S153-5
Unconjugated
MFN2
Liquid
MFN2
Fusion protein amino acids 370-600 (cytoplasmic N-terminus) of mouse Mitofusin-2. Rat: 97% identity (226/231 amino acids identical). Human: 92% identity (214/231 amino acids identical) ∽55% identity with Mitofusin-1.
Protein G
RUO
Antibody
Monoclonal
Human, Mouse, Rat
Documents
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