MFN2 Mouse anti-Human, Mouse, Rat, Clone: S153-5, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA527647
DescriptionThis gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintece and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.
|PBS with 50% glycerol and 0.1% sodium azide; pH 7.4|
|O95140, Q80U63, Q8R500|
|CMT2A, CMT2A2, CPRP 1, CPRP1, Fzo, HSG, hyperplasia suppressor gene, Hypertension related protein 1, KIAA0214, MARF, MFN 2, Mfn2, Mitochondrial assembly regulatory factor, Mitofusin-2, Mitofusin2, Transmembrane GTPase MFN2|
|170731, 64476, 9927|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot|
|Fusion protein amino acids 370-600 (cytoplasmic N-terminus) of mouse Mitofusin-2. Rat: 97% identity (226/231 amino acids identical). Human: 92% identity (214/231 amino acids identical) ∽55% identity with Mitofusin-1.|
|Human, Mouse, Rat|
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