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Invitrogen™ MFSD2A Polyclonal Antibody
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Catalog No. PIPA521049
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100 μg
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Catalog No. Quantity
PIPA521049 100 μg
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Catalog No. PIPA521049 Supplier Invitrogen™ Supplier No. PA521049
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Description

Rabbit Polyclonal Antibody

A suggested positive control is rat lung tissue lysate. PA5-21049 can be used with blocking peptide PEP-1163.

Multidrug transporters, such as MFSD2A, are membrane proteins that expel a wide spectrum of cytotoxic compounds from the cell and render cells resistant to multiple drugs. Major Facilitator Superfamily (MFS) members are capable of transporting various substrates such as sugars, polyols, drugs, neurotransmitters, amino acids, peptides, and inorganic anions, although most members are substrate-specific. MFSD2A is a novel lung cancer tumor suppressor gene that regulates cell cycle progression and matrix attachment and has recently been described as the human receptor for syncytin-2, a retrovirus-derived protein mediating fusion of placental trophoblasts. MFSD2A is expressed in many tissues and is highly induced in liver and brown adipose tissue (BAT) during fasting. The activation of the betaAR signaling pathway plays a major role in the induction of MFSD2A expression during adaptive thermogenesis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MFSD2A
Applications Immunohistochemistry, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene MFSD2A
Gene Accession No. Q8NA29, Q9DA75
Gene Alias 1700018O18Rik; HMFN0656; major facilitator superfamily domain containing 2; major facilitator superfamily domain containing 2A; major facilitator superfamily domain-containing protein 2A; MCPH15; MFSD2; MFSD2A; NLS1; PP9177; RGD1310174; sodium-dependent LPC symporter 1; sodium-dependent lysophosphatidylcholine symporter 1; UNQ300/PRO341; zgc:101615
Gene Symbols MFSD2A
Host Species Rabbit
Immunogen An 18 amino acid peptide near the carboxy terminus of human MFSD2A.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 298504, 76574, 84879
Target Species Human, Mouse, Rat
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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