mGluR1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Catalog No.	Quantity
50-173-2621	150 μL

Catalog No. 50-173-2621 Supplier Proteintech Group Inc Supplier No. 199551AP150UL

Description

Rabbit Polyclonal Antibody

The antibody can recognize isoform1 and isoform2 of GRM1.

Glutamate is the main excitatory neurotransmitter in the brain. For many years it had been considered to act only on the ligand-gated receptor channels-termed NMDA, AMPA and kainite receptors that are involved in the fast excitatory synaptic transmission. Recently, glutamate has been shown to regulate enzymes producing second messengers via specific receptors coupled to G-proteins. These receptors are called metabotropic glutamate receptors. In expression systems, Group-I receptors stimulate phospholipase C as revealed by an increase in phosphoinositide turnover and calcium release from internal stores. Group-II and -III receptors are coupled to the inhibition of adenylyl cyclase. The Group-I receptors include mGluR1a and mGluR5. The Group-II receptors in include mGluR2 and mGluR3.

Specifications

• Antigen: mGluR1
• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
• Classification: Polyclonal
• Concentration: 0.17 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: GRM1
• Gene Accession No.: P97772, Q13255
• Gene Alias: GPRC1A, GRM1, GRM1A, mGlu1, mGluR1, MGLUR1A
• Gene Symbols: GRM1
• Host Species: Rabbit
• Immunogen: Peptide
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 14816, 2911
• Target Species: Human, Mouse
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG